Swiss ADME
Swiss ADME is a free web tool that allows you to compute various properties and parameters of small molecules that are relevant for drug discovery. ADME stands for absorption, distribution, metabolism, and excretion, which are the four main processes that determine the pharmacokinetics of a drug, i.e. how it behaves in the body. Swiss ADME can help you to evaluate the physicochemical descriptors, drug-likeness, medicinal chemistry friendliness, and potential targets of your molecules, as well as to predict their ADME properties, such as permeability, solubility, plasma protein binding, blood-brain barrier penetration, and more. You can use Swiss ADME by entering one or more molecules in SMILES format, or by drawing them using the online sketcher. You can also select a species (human, mouse, or rat) for the target prediction. Swiss ADME will then display the results in a graphical and tabular format, with explanations and references for each parameter. You can also export the results as a CSV file. Swiss ADME is part of the SwissDrugDesign suite of computer-aided drug design tools, which also includes SwissDock, SwissSimilarity, SwissBioisostere, and SwissADME.