CONSULTANCY OFFERED BY NIRMALA COLLEGE OF PHARMACY
The Research & Development Cell is advancing its research facilities to extend our service to industries and other research organizations in the areas:
Cyto-toxicity screening:
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MTT assay
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Apoptotic assay
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Antimitotic activity
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Antiangiogenic activity
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Cell proliferation assay
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RNA isolation and reverse transcription
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Gene expression analysis (RT-PCR)
Anticancer studies (Invitro and invivo):
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Invivo induction of cell line tumors.
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Evaluation of tumors.
Animal studies [Pharmacological screening models]:
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Anti-fertility.
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Anti-inflammatory.
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Antidiabetic.
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Models for neuroprotective and neurodegenerative disorders.
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Laboratory examination and estimation of blood using Autoanalyzer (animals and human).
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Anti- analgesic.
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Anti- convulsion.
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Muscle relaxant.
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Psychological tastings.
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Anti-microbial assay.
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Anti-Ulcer
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Wound healing activities
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Ant- Burn models
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Acute & Chronic Toxicity Studies.
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Hepatotoxicity
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Nephrotoxicity
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Heart/thoracic aorta and CNS toxicity
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Reproductive and Developmental toxicities in rat/mice pups
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Anti-anxiety and Anti-depressant.
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Antidiuretics.
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Anti-malarial.
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Chemical bioassays.
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Anti-mutagenic. (chromosomal abrasion)
Docking studies [by using softwares]
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Chemsketch
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PASS prediction
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ADMET
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Molecular docking with PyRx
PHARMACEUTICAL CHEMISTRY AND ANALYTICAL RESERACH
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Phytochemical Screening and separation of phytochemicals by Column Chromatography.
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Estimation of Phytochemicals.
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Synthesis and identification of bioactive molecules.
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Insilico docking studies on target proteins.
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Drug design.
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Analytical method development and validation of Pharmaceuticals by UV spectrophotometer and HPLC.
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Characterization of organic molecules by IR Spectrophotometry.
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Sample Analysis by FTIR.
PHARMACEUTICAL PREPERATIONS, FORMULATION DEVELOPMENT & EVALUATIONS
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Development of tablets:
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Immediate release tablets.
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Sustained and controlled release tablets.
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Delayed release tablets.
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Quality control test for granules and powders.
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Preparation of Hard Gelatin capsules.
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Development of coated tablets.
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Development of pellets.
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Development of semisolids and cosmetic preparations.
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All Quality control test for capsules and tablets.
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Microbial Assays.
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Antibiotic sensitivity studies.
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Leak test for ampoules, vials and other primary packing materials.
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Development and evaluation of liquid dosage forms-syrup, suspensions and emulsions.
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Accelerated stability studies for pharmaceutical dosage forms.
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Drug -Excipients compatibility studies.
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Phase solubility studies.
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Formulation development using computational methods- QbD, BOE(Design expert).
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Statistical Analysis.
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Development of novel Drug Delivery systems-Liposomes, Neosomes , transferosomes.
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Bioavailability studies in animal models.
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Pharmacokinetic calculations using computational techniques.
PHARMACOGNOSTICAL RESERACH
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Hot continuous extraction technique by soxhlet apparatus for crude extracts using various solvent systems.
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TLC method development for herbal substances, herbal Drugs , herbal formulations and ayurvedic formulations.
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Standardization of herbal materials by Physical and Chemical methods like ash value, extractive values, loss on drying and Phytochemical Tests.
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Analytical Evaluation of edible oils by acid value, saponification value ,ester value and iodine value.